Psychological, Social, and Economic Difficulties in Patients with Alzheimer's Disease (AD) in a Population in Southern Colombia
DOI:
https://doi.org/10.31052/1853.1180.v30.n2.42613Keywords:
Alzheimer's disease, Anxiety, Depression, Economic difficultiesAbstract
Introduction: Population aging is a care priority in public health, especially age-related dementia disorders, with Alzheimer's disease (AD) being the leading cause of dementia in the elderly. Psychological and behavioral symptoms are present in the majority of patients with AD, affecting all areas, including functionality. AD patients need assistance with daily activities and medical care, leading to severe psychological and economic stress for both the patient and the caregiver.
Objective: To identify the psychological, social, and economic difficulties of patients with AD in a population in southern Colombia in 2021.
Methodology: This observational, descriptive, cross-sectional study included 30 AD patients at any disease stage who met the inclusion criteria and participated voluntarily between May 1 and September 30, 2021. Caregivers were interviewed using a structured survey to collect personal, economic, social, and psychological information about the AD patient.
Results: The study population was characterized by an age range of 70-79 years, predominantly male, and low socioeconomic status. Late-onset AD was present in 40% of patients. The most common psychological difficulties were depression (23%), followed by anxiety (17%) and memory issues. Regarding social difficulties, 43% only had social ties with their caregiver, and 73% had low educational levels. Economically, 53% had low monthly incomes and required significant family financial support to manage the disease. Early-onset AD patients had higher depression rates, whereas late-onset patients experienced more anxiety.
Conclusion: The study concludes that patients with AD face psychological challenges, such as depression in early stages and anxiety in late stages, comorbidities, and mental functioning issues, especially in memory and mobility, which increase cognitive decline. Identifying social and economic difficulties is essential for disease management and safeguarding patient and caregiver well-being.
Downloads
References
Organización Panamericana de la Salud. Demencia: una prioridad de salud pública - OPS/OMS | Organización Panamericana de la Salud [Internet]. 2021 [citado 29 de mayo de 2024]. Disponible en: https://www.paho.org/es/documentos/demencia-prioridad-salud-publica
Organización Mundial de la Salud. Demencia. 2023. [Internet]. [citado 29 de mayo de 2024]. Disponible en: https://www.who.int/es/news-room/fact-sheets/detail/dementia
Sousa MFB, Santos RL, Nogueira ML, Belfort T, Rosa RDL, Torres B, et al. Awareness of disease is different for cognitive and functional aspects in mild Alzheimer’s disease: a one-year observation study. J Alzheimers Dis. 2015;43(3):905-13.
Barbe C, Morrone I, Wolak-Thierry A, Dramé M, Jolly D, Novella JL, et al. Impact of functional alterations on quality of life in patients with Alzheimer’s disease: Aging & Mental Health. 2016; 21(5):571-576.
Perez Romero A, González Garrido S. La importancia de los síntomas psicológicos y conductuales (SPCD) en la enfermedad de Alzheimer. Neurología. 2018; 33(6):378-384.
Wilz G, Weise L, Reiter C, Reder M, Machmer A, Soellner R. Intervention Helps Family Caregivers of People With Dementia Attain Own Therapy Goals. Am J Alzheimers Dis Other Demen. 2018;33(5):301-8.
Cavallo F, Aquilano M, Arvati M. An Ambient Assisted Living Approach in Designing Domiciliary Services Combined With Innovative Technologies for Patients With Alzheimer’s Disease. Am J Alzheimers Dis Other Demen. 2015;30(1):69-77.
Rodriguez G, De Leo C, Girtler N, Vitali P, Grossi E, Nobili F. Psychological and social aspects in management of Alzheimer’s patients: an inquiry among caregivers. Neurol Sci. 2003;24(5):329-35.
Issue Information-Declaration of Helsinki. J Bone Miner Res. 2017;32(9):BM i-BM ii.
Soria Lopez JA, González HM, Léger GC. Alzheimer’s disease. En: Handbook of Clinical Neurology [Internet]. Elsevier; 2019 [citado 3 de junio de 2024]. p. 231-55. Disponible en: https://linkinghub.elsevier.com/retrieve/pii/B9780128047668000133
Li R, Singh M. Sex Differences in Cognitive Impairment and Alzheimer’s Disease. Front Neuroendocrinol. 014;35(3):385-403.
Chen CY an, Chiu CC, Huang CY, Cheng YC, Huang MC, Kuo PH, et al. Cluster analysis dissecting cognitive deficits in older adults with major depressive disorder and the association with neurofilament light chain. BMC Geriatr. 2024;24:344.
Cole S, Hua C, Peng S, Wang W. Exploring the Relationship of Leisure Travel with Loneliness, Depression, and Cognitive Function in Older Adults. Int J Environ Res Public Health. 2024;21(4):498.
Burke SL, Cadet T, Alcide A, O’Driscoll J, Maramaldi P. Psychosocial risk factors and Alzheimer’s disease: the associative effect of depression, sleep disturbance, and anxiety. Aging Ment Health. 2018;22(12):1577-84.
15.Botto R, Callai N, Cermelli A, Causarano L, Rainero I. Anxiety and depression in Alzheimer’s disease: a systematic review of pathogenetic mechanisms and relation to cognitive decline. Neurol Sci. 2022;43(7):4107-4124.
Burke AD, Goldfarb D, Bollam P, Khokher S. Diagnosing and Treating Depression in Patients with Alzheimer’s Disease. Neurol Ther. 2019;8(2):325-50.
Zhang XX, Tian Y, Wang ZT, Ma YH, Tan L, Yu JT. The Epidemiology of Alzheimer’s Disease Modifiable Risk Factors and Prevention. J Prev Alzheimers Dis. 2021;8(3):313-21.
Marseglia A, Dahl Aslan AK, Fratiglioni L, Santoni G, Pedersen NL, Xu W. Cognitive Trajectories of Older Adults With Prediabetes and Diabetes: A Population-Based Cohort Study. J Gerontol A Biol Sci Med Sci. 2018;73(3):400-406.
Oishi E, Ohara T, Sakata S, Fukuhara M, Hata J, Yoshida D, et al. Day-to-Day Blood Pressure Variability and Risk of Dementia in a General Japanese Elderly Population: The Hisayama Study. Circulation. 2017;136(6):516-25.
Tolppanen AM, Ngandu T, Kåreholt I, Laatikainen T, Rusanen M, Soininen H, et al. Midlife and late-life body mass index and late-life dementia: results from a prospective population-based cohort. J Alzheimers Dis. 2014;38(1):201-209.
Sommerlad A, Sabia S, Singh-Manoux A, Lewis G, Livingston G. Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study. PLoS Med. 2019;16(8):e1002862.
Mozersky J, Davis DS. Living with Alzheimer Disease and Other Types of Dementia: Stories from Caregivers. Narrat Inq Bioeth. 2020;10(2):89-93.
Bennett D, Wilson R, Schneider J, Evans D, Mendes de Leon C, Arnold S, et al. Education modifies the relation of AD pathology to level of cognitive function in older persons. Neurology. 2003;60(12):1909-1915.
EClipSE Collaborative Members, Brayne C, Ince PG, Keage HAD, McKeith IG, Matthews FE, et al. Education, the brain and dementia: neuroprotection or compensation? Brain. 2010;133(Pt 8):2210-6.
Meng Xiangfei, D´Arcy C.Educatio n and dementia in the context of the cognitive reserve hypothesis: a systematic review with meta-analyses and qualitative analyses. PloS one. 2012;7(6):e38268.
Winston Wong P. Economic Burden of Alzheimer Disease and Managed Care Considerations. Am J Manag Care. 2020;26:S177-S183.
2022 Alzheimer’s disease facts and figures. Alzheimer’s & Dementia. 2022;18(4):700-89.
Jones RW, Lebrec J, Kahle-Wrobleski K, Dell’Agnello G, Bruno G, Vellas B, et al. Disease Progression in Mild Dementia due to Alzheimer Disease in an 18-Month Observational Study (GERAS): The Impact on Costs and Caregiver Outcomes. Dement Geriatr Cogn Dis Extra. 2017;7(1):87-100.
2023 Alzheimer’s disease facts and figures. Alzheimer’s & Dementia. 2023;19(4):1598-695.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Escuela de Salud Pública y Ambiente. Facultad de Ciencias Médicas. Universidad Nacional de Córdoba
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License which allows the work to be copied, distributed, exhibited and interpreted as long as it is not done for commercial purposes.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) after the publication process. (See The Effect of Open Access). (See The Effect of Open Access).