Neuroanatomical and functional substrates of the medial prefrontal cortex

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Published: Jan 16, 2019
DOI: https://doi.org/10.32348/1852.4206.v10.n3.20619
Keywords:
behavior, infralimbic cortex, medial prefrontal cortex, prelimbic cortex

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Jorge Alexander Ríos Flórez
Universidade Federal do Rio Grande do Norte. Grupo de Investigación en Neurociencias Hippocampus
http://orcid.org/0000-0002-8367-8225

Abstract

This article presents how a revision that was done sought out to integrate the updated knowledge that we have about neuroanatomical and morphological substrates of the functional circuits that the medial prefrontal cortex (mPFC) establishes with other brain structures. Several investigations have described the emergent and/or convergent projections of the mPFC, mainly taking rodents as a study model; using the technique of neuronal marker as the main technique of inquiry to reveal such projections, followed by works that propose electrophysiography to reveal the cerebral connectivity. Thus, the interaction of the mPFC with other brain structures has been described, among which the hippocampus, the periaqueductal gray matter, the hypothalamus, the nucleus accumbens, the cerebral amygdala, the ventral tegmental area, the dorsal nucleus of Rafe and the lateral habenula of the epithalamus, among others. These investigations have gone beyond the physical component of brain connectivity, extrapolating and enabling the functional understanding of the anatomical pathways established between the different regions interrelated with the mPFC, revealing the cognitive-behavioral activity of the study subjects.

Article Details

How to Cite
Neuroanatomical and functional substrates of the medial prefrontal cortex. (2019). Argentinean Journal of Behavioral Sciences, 10(3), 43-53. https://doi.org/10.32348/1852.4206.v10.n3.20619
Issue
Vol. 10 No. 3 (2018): REVISTA ARGENTINA DE CIENCIAS DEL COMPORTAMIENTO
Section
Reviews

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Author Biography

Jorge Alexander Ríos Flórez, Universidade Federal do Rio Grande do Norte. Grupo de Investigación en Neurociencias Hippocampus

Docente-Investigador. Director del Grupo de Investigación en Neurociencias Hippocampus; Psicólogo, Universidad Pontificia Bolivariana, Especialista en Evaluación y Diagnóstico Neuropsicológico, Magíster en Neuropsicología clínica, Universidad de San Buenaventura, Bogotá, D.C., Colombia. Miembro del Grupo Psicología, Educación y Cultura de la Institución Universitaria Politécnico Grancolombiano. Doctorando en Psicobiología, Universidade Federal do Rio Grande do Norte, Brasil.

How to Cite

Neuroanatomical and functional substrates of the medial prefrontal cortex. (2019). Argentinean Journal of Behavioral Sciences, 10(3), 43-53. https://doi.org/10.32348/1852.4206.v10.n3.20619

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