Prenatal association between a chemosensory cue (cineole) and ethanol postabsortive effects modulates later operant responsiveness to cineole-flavored milk in 1 day old rats

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Published: Jul 28, 2011
DOI: https://doi.org/10.32348/1852.4206.v3.n2.5224
Keywords:
fetal learning, ethanol, reinforcement, conditioning

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Samanta Mabel March
Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra
Paula Abate
Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra
Juan Carlos Molina
Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra

Abstract

Near-term rat fetuses detect and associate ethanol’s sensory and postabsortive properties. We aimed to evaluate changes upon operant conditioning in neonates, as a function of prenatal ethanol-mediated associative experiences. Prenatal treatments were: Paired group, dams administered (i.g.) with cineole and 15-min later with EtOH (2.0 g/kg); Long-delay group, dams received cineole 6 hours before ethanol intoxication; Water group, dams received two administrations of water separated by 15 min. On PD1 neonates were trained in an operant task. Two different learning conditions were used. Paired pups were trained under a FR=1 reinforcement schedule. Yoked pups received the reinforcer but, unrelated to their own behavior. Milk or Cineole-flavored milk were the reinforce solutions. Present results support the idea that ethanol-related prenatal memories modulate operant responsiveness when pups are reexposed to cues that predict toxic consequences of the drug..

Article Details

How to Cite
Prenatal association between a chemosensory cue (cineole) and ethanol postabsortive effects modulates later operant responsiveness to cineole-flavored milk in 1 day old rats. (2011). Argentinean Journal of Behavioral Sciences, 3(2), 12-18. https://doi.org/10.32348/1852.4206.v3.n2.5224
Issue
Vol 3, No 2 (2011): Revista Argentina de Ciencias del Comportamiento
Section
Original Articles

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Author Biographies

Samanta Mabel March, Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra

Facultad de Psicología, Universidad Nacional de Córdoba.

Paula Abate, Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra

Facultad de Psicología, Universidad Nacional de Córdoba

How to Cite

Prenatal association between a chemosensory cue (cineole) and ethanol postabsortive effects modulates later operant responsiveness to cineole-flavored milk in 1 day old rats. (2011). Argentinean Journal of Behavioral Sciences, 3(2), 12-18. https://doi.org/10.32348/1852.4206.v3.n2.5224

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