Alcohol-related problems: neurobiological bases of alcohol consumption and animal models developed to address these problems

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Published: Sep 2, 2009
DOI: https://doi.org/10.32348/1852.4206.v1.n1.5302
Keywords:
rat, alcohol, opiate system, genetic models

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Samanta M. March
Instituto Ferreyra
Roberto Sebastián Miranda Morales
Instituto Ferreyra

Abstract

The present review is focused on animal models for the study of alcohol use, abuse and dependence. These models have helped to understand several features of alcohol consumption, ranging from genetic influences to environmental factors such us early experiences with the drug. Additionally, animal models have been useful tools to assess the efficacy of pharmacological treatments as well as alcohol associated phenomena, such as craving, tolerance and reinstatement. First we introduce a short description of the neurobiological basis of alcohol reinforcement, focused on the opiate system. Then we cover several animal models, from genetic models, and models focused on the study of alcohol related disorders to animal models that emphasize the importance of early experiences with the drug in the development of alcohol use and alcohol related disorders.

Article Details

How to Cite
Alcohol-related problems: neurobiological bases of alcohol consumption and animal models developed to address these problems. (2009). Argentinean Journal of Behavioral Sciences, 1(1), 36-50. https://doi.org/10.32348/1852.4206.v1.n1.5302
Issue
Vol 1, No 1 (2009): Revista Argentina de Ciencias del Comportamiento
Section
Reviews

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Author Biographies

Samanta M. March, Instituto Ferreyra

Facultad de Psicología, Universidad Nacional de Córdoba, Córdoba, Argentina.

Roberto Sebastián Miranda Morales, Instituto Ferreyra

Facultad de Psicología, Universidad Nacional de Córdoba, Córdoba, Argentina.

How to Cite

Alcohol-related problems: neurobiological bases of alcohol consumption and animal models developed to address these problems. (2009). Argentinean Journal of Behavioral Sciences, 1(1), 36-50. https://doi.org/10.32348/1852.4206.v1.n1.5302

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