B cell lyphoma mimicking rheumatoid arthritis, a case report
DOI:
https://doi.org/10.31053/1853.0605.v73.n1.12539Keywords:
polyartrithis, non hodking`s lymphoma, skin rashAbstract
Non Hodking´s lymphoma (NHL) may involve bones but synovial involvement is uncommon. We describe a patient who presented with polyarthritis, sicca symptoms and rash suggestive of rheumatoid arthritis. An atypical skin rash prompted skin and synovial biopsies. A diagnosis of synovial and skin malignant large B-cell lymphoma anaplastic subtype was performed. Chemotherapy with dexamethasone, vincristine and rituximab was started. Following treatment the patient had complete resolution of cutaneous and articular lymphoma manifestations.
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1- Howard D. Dorfman, Howard L. Siegel, Michael C. Perry, Ronald Oxenhandler. Non-hodgkin’s lymphoma of the synovium simulating rheumatoid arthritis. Arthritis Rheum 1987; Vol: 30 No. 2: 155-160.
2- Merih Birlik, Servet Akar, Fatos Onen, Mehmet Ali Ozcan, Abdulkadir Bacakoglu, Sermin Ozkal, et al. Articular, B-cell, non-Hodgkin’s lymphoma mimicking rheumatoid arthritis: synovial involvement in a small hand joint. Rheumatol Int 2004; 24: 169–172.
3- V. M. Martin, R. M. Bennett, G. R. V. Hughes, P. J. L. Holt. Lymphosarcomatous arthropathy .Ann Rheum Dis. 1973; 32: 162-166.
4- N Menon, R Madhok. Symmetrical polyarthritis is not always rheumatoid. Ann Rheum Dis. 1994; 53: 631-632.
5- J. E. Mcdonagh, F. Clarke, S. R. Smith, P. Kesteven, J. Walker. Non-hodgkin's lymphoma presenting as polyarthritis. Rheumatology (Oxford) 1994;33:79-84.
6- Roldan MR, Martinez F, Roman J, Torres A. Non-Hodgkin's lymphoma: initial manifestation. Ann Rheum Dis. 1993;52:85-6.
7- Bert Lincoln Pear. Skeletal Manifestations of the Lymphomas and Leukemias. Semin Roentgenol 1974; Vol. IX. No: 3: 229-240.
8- Ethan M. Braunsteln, Susan J. White. Non-Hodgkin Lymphoma of Bone. Radiology 1980,135:59-63.
9- Jetze Visser, Vincent JJF Busch, Ineke M de Kievit-van der Heijden, Arno M ten Ham. Non-Hodgkin’s Lymphoma of the synovium discovered in total knee arthroplasty: a case report. BMC Research Notes 2012; 5:449.
10- Adunsky A, Yaretzky A, Klajman A: Malignant lymphoma presenting as sternoclavicular joint arthritis (letter). Arthritis Rheum 1980; 23:1330-1331.
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