Edad materna avanzada como factor de riesgo de resultados adversos maternos y perinatales

Maria Eugenia Carducci; Gustavo Izbizky

doi:10.31053/1853.0605.v81.n1.41447

Authors

Maria Eugenia Carducci Servicio de Obstetricia, Hospital Italiano de Buenos Aires. Instituto Universitario del Hospital Italiano de Buenos Aires.
Gustavo Izbizky Servicio de Obstetricia, Hospital Italiano de Buenos Aires. Instituto Universitario del Hospital Italiano de Buenos Aires.

DOI:

https://doi.org/10.31053/1853.0605.v81.n1.41447

Keywords:

maternal age , pregnancy complications , pregnancy outcome , perinatal care

Abstract

Introduction: A progressive increase in the age of women at first pregnancy is observed, a situation that has been associated with a greater risk of adverse maternal and perinatal effects.

Objective: The aim of this study was to describe the characteristics and the maternal and perinatal outcomes of nulliparas of 40 years and older and compare them with those of nulliparas under 40.

Study design: This was a retrospective cohort analysis of a database of pregnancy population who had attended their deliveries in a private university hospital.

Results: An association was observed between maternal age ≥ 40 with the maternal compound adverse outcome (OR 1,3; 95% CI: 1,1-1,6), gestational diabetes (OR 3,6; 95% CI: 1,80-3,7), hypertensive disorders/preeclampsia (OR 2,2; 95% CI: 1,6-3,1) and postpartum hemorrhage (4,7; 95% CI: 1,2-16,3), with advanced maternal age persisting as an independent risk factor for the maternal compound adverse outcome (OR 1,3; 95% CI: 1,1 -1,6) and the perinatal compound adverse outcome (OR 1,40; 95% CI: 1,2-1,7) in the multivariate analysis. A higher rate of preterm birth was observed in the group of older nulliparas (OR 1,6; 95% CI: 1,3-2,0) with a higher requirement for admission to NICU for their newborns (OR 1,3; 95% CI: 1,0-1,8).

Conclusions: Women with advanced maternal age constitute a high-risk population, whose attention and follow-up would require a differential approach aiming to improve maternal and perinatal outcomes.

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Author Biographies

Maria Eugenia Carducci, Servicio de Obstetricia, Hospital Italiano de Buenos Aires. Instituto Universitario del Hospital Italiano de Buenos Aires.

She is a doctor received from the Faculty of Medicine of the UBA with an Honors Diploma, specialist in Tocogynecology, subspecialist in Maternal Fetal Medicine, Master in Sexual and Reproductive Health (UNC) and master's candidate in Health Informatics. Professor assigned to the UBA and Assistant of Practical Works of the Tocogynecological Clinic of the University Institute of the Italian Hospital of Buenos Aires. She works as Coordinator of the Maternal Fetal Medicine Section at the Italian Hospital of San Justo.
Gustavo Izbizky, Servicio de Obstetricia, Hospital Italiano de Buenos Aires. Instituto Universitario del Hospital Italiano de Buenos Aires.

He is a doctor received from the Faculty of Medicine of the UBA with an Honors Diploma, specialist in Tocogynecology, Master in Clinical Effectiveness (UBA). He carries out teaching tasks as Associate Professor of the Tocogynecological Clinic, University Institute of the Italian Hospital of Buenos Aires, and Authorized Teacher UBA. In the field of care, he works as a doctor at the Obstetrics Service Hospital Italiano de Buenos Aires, having been Acting Head of the Obstetrics Service Hospital Italiano de Buenos Aires. He has extensive experience in clinical research, having been Coordinator of the Ethics Committee of Research Protocols Hospital Italiano de Buenos Aires.

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